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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC1L All Species: 12.12
Human Site: S255 Identified Species: 22.22
UniProt: Q13415 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13415 NP_004144.2 861 97350 S255 S Q Q T S C A S L D S P G R I
Chimpanzee Pan troglodytes XP_513408 861 97367 S255 S Q Q T S C A S L D S P G R I
Rhesus Macaque Macaca mulatta XP_001111614 860 97440 S255 S Q Q T S R A S L D S P G R M
Dog Lupus familis XP_532575 858 97161 L253 S Q Q N S G A L L D S P G R S
Cat Felis silvestris
Mouse Mus musculus Q9Z1N2 840 95057 S234 V I P S A K K S L E L D G L G
Rat Rattus norvegicus Q80Z32 848 95741 L249 M R L S R K I L C D S L D S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026457 858 96850 T257 K L E L N S P T R S P K S K L
Frog Xenopus laevis NP_001081806 886 99953 K262 L Q L S S P T K S E V S S L E
Zebra Danio Brachydanio rerio NP_956227 910 101179 I295 N S S P S G R I S I S I R L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16810 924 103263 L276 G G R S V V R L S E K K N A P
Honey Bee Apis mellifera XP_392056 490 55682
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798977 905 100707 V267 K P T P K M S V A K E T K A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567440 809 91877 P223 G Q T L V V V P K P P E G K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.7 81.5 N.A. 66 69.8 N.A. N.A. 50.5 52.4 48.6 N.A. 33.4 31.8 N.A. 29.7
Protein Similarity: 100 98.9 97.3 88.8 N.A. 77.9 79.9 N.A. N.A. 66.3 67 63.1 N.A. 52.7 43.5 N.A. 47.1
P-Site Identity: 100 100 86.6 73.3 N.A. 20 13.3 N.A. N.A. 0 13.3 13.3 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 93.3 73.3 N.A. 40 26.6 N.A. N.A. 33.3 26.6 20 N.A. 20 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 27.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 31 0 8 0 0 0 0 16 0 % A
% Cys: 0 0 0 0 0 16 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 39 0 8 8 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 24 8 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 8 0 0 0 16 0 0 0 0 0 0 47 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 8 0 8 0 8 0 0 16 % I
% Lys: 16 0 0 0 8 16 8 8 8 8 8 16 8 16 8 % K
% Leu: 8 8 16 16 0 0 0 24 39 0 8 8 0 24 8 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 8 8 16 0 8 8 8 0 8 16 31 0 0 8 % P
% Gln: 0 47 31 0 0 0 0 0 0 0 0 0 0 0 16 % Q
% Arg: 0 8 8 0 8 8 16 0 8 0 0 0 8 31 0 % R
% Ser: 31 8 8 31 47 8 8 31 24 8 47 8 16 8 8 % S
% Thr: 0 0 16 24 0 0 8 8 0 0 0 8 0 0 8 % T
% Val: 8 0 0 0 16 16 8 8 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _